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[Fluorosis. Experiences based on two cases]
I Tollefsen1, G Duus, F Johannessen
1Røntgenavdelingen, Sentralsjukehuset i Rogaland, Stavanger.
Summary
Sodium fluoride treatment for osteoporosis showed benefits in pain and fracture reduction over many years. However, delayed diagnosis of skeletal fluorosis led to unnecessary cancer screenings in two patients.
Area of Science:
- Endocrinology
- Radiology
- Bone Metabolism
Background:
- Sodium fluoride has been used since 1961 for osteoporosis treatment, but its efficacy on pain and vertebral fractures remains debated among endocrinologists.
- Long-term treatment of postmenopausal osteoporosis with calcium, vitamin D, and sodium fluoride was investigated.
Observation:
- Two cases of postmenopausal osteoporosis treated for many years with calcium, vitamin D, and sodium fluoride are presented.
- Both patients experienced positive effects on pain and a reduced tendency for lumbar vertebral body fractures.
Findings:
- The diagnosis of skeletal fluorosis was delayed in both patients for several years.
- Delayed diagnosis occurred because radiologists were not informed about the sodium fluoride treatment, leading to misdiagnosis and unnecessary investigations for suspected cancer metastasis.
Implications:
- This case report highlights the importance of clear communication between referring physicians and radiologists regarding patient treatments.
- Improved diagnostic awareness and communication are crucial to prevent delayed diagnoses of conditions like skeletal fluorosis and avoid unnecessary medical procedures.