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Published on: March 13, 2015
[Hepatitis epidemic among drug addicts in Esbjerg from July 1993 to May 1994]
1Medicinsk afdeling, Centralsygehuset i Esbjerg.
Insights
An outbreak of acute viral hepatitis (A, B, and C) occurred in Esbjerg, Denmark, primarily affecting intravenous drug users. This highlights the risk of parenteral transmission and the need for harm reduction strategies.
Area of Science:
- Hepatology
- Infectious Diseases
- Public Health
Context:
- An 11-month period (July 1993-May 1994) in Esbjerg, Denmark, saw a significant increase in acute viral hepatitis cases.
- Typically, only 1-3 patients are admitted annually for acute viral hepatitis.
- 16 out of 19 patients reported intravenous drug use, with some using drugs sporadically.
Purpose:
- To investigate an unusual cluster of acute viral hepatitis cases.
- To identify the types and combinations of hepatitis viruses involved.
- To explore potential transmission routes, particularly parenteral transmission, in a specific patient group.
Summary:
- 19 patients presented with acute hepatitis A, B, and/or C.
- Hepatitis B in patients positive for hepatitis C antibodies was the most frequent combination.
- Hepatitis A occurrence suggested parenteral transmission; no HIV antibodies were detected in tested patients.
Impact:
- The study documented an epidemic of acute viral hepatitis in Esbjerg.
- It underscored the link between intravenous drug use and viral hepatitis transmission.
- A clean needle and syringe vending machine was installed post-epidemic, indicating a public health response.
Abstract:
During 11 months from July 1993 to May 1994 the Department of Internal Medicine at Esbjerg Centralsygehus saw 19 patients with acute hepatitis A, B and/or C. In a normal year one to three patients are admitted with acute viral hepatitis. Sixteen of the patients reported intravenous drug use, half of them only sporadically, i.e. once or twice a month. Acute hepatitis A, B and C were seen in seven different combinations, the most frequent being acute hepatitis B in a hepatitis C antibody positive patient. The occurrence of acute hepatitis A in this group of patients may be due to parenteral transmission. Among 10 patients tested for HIV antibodies, none were found to be positive. In Esbjerg, which is the fifth largest city in Denmark, an automat with clean needles and syringes was installed six months after the culmination of the epidemic.
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