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Closantel intoxication in a dog
K McEntee1, M Grauwels, C Clercx
1Small Animal Clinic, Department of Internal Medicine, Faculty of Veterinary Medicine, University of Liege, Belgium.
Veterinary and Human Toxicology
|June 1, 1995
Abstract:
A case of overdosage with closantel, a salicynalide derivative, in a dog is described. The dog received 6 times the recommended dosage. Closantel induced optic neuritis, retinal degeneration, partial deafness, hepatotoxicosis and myopathy. Only the blindness was irreversible. The therapy included albumin administration to reduce the acute toxicity of closantel.