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Male breast cancer: Austrian experience
M Stierer1, H Rosen, W Weitensfelder
1Department of Surgery, Hanusch Medical Center, Vienna, Austria.
World Journal of Surgery
|September 1, 1995
Summary
This study on male breast cancer found that tumor size and lymph node status significantly impact recurrence and survival. Advanced stages were common, affecting overall outcomes despite comparable stage-adjusted data to female breast cancer.
Area of Science:
- Oncology
- Surgical Oncology
- Male Breast Cancer Research
Background:
- Male breast cancer is rare, with limited data on prognostic factors.
- Previous studies suggest similarities to female breast cancer, but outcomes may differ due to stage at diagnosis.
Purpose of the Study:
- To analyze clinical features and prognostic factors in a cohort of men treated for breast cancer.
- To assess the impact of tumor size and axillary lymph node status on recurrence-free and overall survival.
Main Methods:
- Retrospective analysis of data from 169 male breast cancer patients treated between 1970 and 1991 in Austria.
- Evaluation of established prognostic factors including tumor size and axillary lymph node status.
- Multivariate analysis to determine independent prognostic significance.
Main Results:
- A 5-year recurrence-free survival of 55% and overall survival of 62% were estimated.
- Tumor size and axillary lymph node status were significant prognostic factors for recurrence-free and overall survival (p < 0.0001).
- Axillary lymph node status remained a significant independent prognostic factor in multivariate analysis (p < 0.01).
Conclusions:
- Tumor size and axillary lymph node status are critical prognostic indicators in male breast cancer.
- The high frequency of advanced tumor stages in this cohort may explain the observed survival rates.
- Surgical procedures did not influence local recurrence rates.