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[Primary hypertrophic osteoarthropathy]

A Eckardt1, K F Kreitner

  • 1Orthopädische Univ.-Klinik Mainz.

Zeitschrift Fur Orthopadie Und Ihre Grenzgebiete
|July 1, 1995
PubMed
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This report details a rare case of primary hypertrophic osteoarthropathy (Touraine-Solente-Golé Syndrome). This syndrome is a rare cause of chronic bone and joint pain, distinct from secondary forms.

Area of Science:

  • Rheumatology
  • Medical Genetics
  • Radiology

Background:

  • Primary hypertrophic osteoarthropathy, also known as Touraine-Solente-Golé Syndrome, is an exceptionally rare condition.
  • It is characterized by specific bone and skin changes, often presenting as chronic joint and limb pain.

Observation:

  • A middle-aged woman presented with over twenty years of chronic joint and limb pain.
  • Diagnostic imaging revealed cortical thickening of tubular bones, craniosclerosis, periosteal reactions, facial skin thickening, and digital clubbing.
  • Pulmonary involvement, indicative of secondary pulmonary osteoarthropathy (Pierre-Marie-Bamberger's Syndrome), was ruled out.

Findings:

  • The case exemplifies Touraine-Solente-Golé Syndrome, a rare subtype of hypertrophic osteoarthropathy.

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  • This specific syndrome accounts for only 3-5% of all hypertrophic osteoarthropathy cases.
  • Key radiological findings included bone thickening and sclerosis, consistent with the syndrome.

    • Implications:

    • Highlights the importance of considering rare differential diagnoses for chronic bone and joint pain.
    • Emphasizes the diagnostic value of combining clinical presentation with advanced imaging techniques.
    • Contributes to the understanding and recognition of Touraine-Solente-Golé Syndrome in clinical practice.