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Ureteropelvic fungal bezoar causing oliguric renal failure in a premature infant

K T Wu1, W F Chen, L M Chiang

  • 1Department of Pediatrics, Chang Gung Memorial Hospital, Kaohsiung, Taiwan, R.O.C.

Zhonghua Minguo Xiao Er Ke Yi Xue Hui Za Zhi [Journal]. Zhonghua Minguo Xiao Er Ke Yi Xue Hui
|July 1, 1995
PubMed

Insights

Systemic candidiasis can cause rare kidney problems in infants. Early detection of fungal balls obstructing the urinary tract is crucial for timely intervention and improved outcomes in high-risk infants.

Area of Science:

  • Pediatric Infectious Diseases
  • Neonatal Nephrology

Background:

  • Systemic candidiasis is uncommon in neonates, particularly with significant renal involvement.
  • Aggressive management has historically improved survival rates in reported cases.

Observation:

  • A three-month-old premature infant presented with fatal systemic candidiasis and acute renal failure.
  • Renal pelvic fungal balls were identified as the cause of ureteropelvic junction obstruction.
  • Renal ultrasonography revealed bilateral obstructive uropathy.

Findings:

  • The infant's condition involved obstruction of the urinary tract by fungal bezoars.
  • Treatment included surgical removal of fungal balls, nephrostomy tube placement, amphotericin B, and peritoneal dialysis.

Implications:

  • This case highlights the critical need for high suspicion of fungal ball obstruction in infants with systemic candidiasis and renal dysfunction.
  • Prompt diagnosis and intervention are vital for managing this rare but severe complication in high-risk neonates.

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