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[Anaphylaxis caused by royal jelly]

A Roger1, N Rubira, C Nogueiras

  • 1Servicio de Alergia, Hospital General Vall d'Hebron, Universitat Autónoma de Barcelona.

Allergologia Et Immunopathologia
|May 1, 1995
PubMed
Summary

This study details the first documented case of an IgE-mediated anaphylactic reaction to royal jelly. A 15-year-old experienced severe allergic symptoms after consuming royal jelly, highlighting potential risks.

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Area of Science:

  • Allergy and Immunology
  • Food Science
  • Toxicology

Background:

  • Royal jelly, a bee secretion, is marketed for purported health benefits, including rejuvenation.
  • Its potential allergenicity in humans remains largely uncharacterized in medical literature.

Observation:

  • A 15-year-old atopic patient developed immediate, severe allergic symptoms including angioedema, urticaria, dysphonia, and bronchospasm after royal jelly ingestion.
  • Standard allergy tests for common allergens were negative, but specific IgE testing for royal jelly was positive.

Findings:

  • The patient exhibited a positive prick test to royal jelly and elevated total IgE levels.
  • The reaction was consistent with an IgE-mediated anaphylactic response specifically attributed to royal jelly.

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Implications:

  • This case represents the first reported instance of royal jelly allergy causing anaphylaxis.
  • Highlights the need for increased awareness of royal jelly as a potential allergen and for further research into its immunogenic properties.