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Murine Model of Allergen Induced Asthma
08:05

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

Vineyard snail allergy possibly induced by sensitization to house-dust mite (Dermatophagoides pteronyssinus)

F De Maat-Bleeker1, J H Akkerdaas, R van Ree

  • 1Department of Dermatology and Allergology, University Hospital, Utrecht, The Netherlands.

Allergy
|May 1, 1995
PubMed

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Delayed-Type Hypersensitivity (DTH), or Type IV hypersensitivity, is a cell-mediated immune response. It occurs when T cells, rather than antibodies, mediate a reaction to specific antigens. It is characterized by a delayed onset (1-2 days) and involves the recruitment of macrophages to the inflammation site.The initiation of a DTH response begins with the sensitization of T cells. During this phase, which lasts at least 1-2 weeks, antigen-specific T cells are activated, clonally expanded, and...