Well differentiated neuroendocrine carcinoma of the breast. A case report

A neuroendocrine breast carcinoma occurring in a 79 year-old woman is presented. The case presented typically as a single nodule in the upper and outer quadrant of her right breast and showed a pure histology consisting exclusively of organoid nests of well differentiated cells that mimicked those of carcinoid tumors of the lung. The literature is briefly reviewed and commented. In the light of this review, we conclude that the issue of carcinomas with neuroendocrine differentiation in breast pathology is controversial and its terminology somewhat debatable.