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Published on: February 16, 2016
Left ventricular end-systolic volume index in patients with ischemic cardiomyopathy predicts postoperative
1Department of Cardiovascular Surgery, Jichi Medical School, Omiya Medical Center, Saitama, Japan.
Insights
Preoperative left ventricular end-systolic volume index (LVESVI) predicts recovery of heart function after bypass surgery. A lower LVESVI (<100 mL/m2) indicates better outcomes in ischemic cardiomyopathy patients.
Area of Science:
- Cardiology
- Cardiac Surgery
- Cardiovascular Imaging
Background:
- Assessing postoperative ventricular function is crucial for patients undergoing coronary artery bypass grafting (CABG).
- Preoperative left ventricular end-systolic volume index (LVESVI) is explored as a potential predictor of cardiac recovery.
- Ischemic cardiomyopathy with low ejection fraction presents a challenge for surgical outcomes.
Purpose of the Study:
- To evaluate the predictive value of preoperative LVESVI for postoperative ventricular function.
- To determine if LVESVI can identify patients likely to benefit from CABG despite severely impaired ejection fraction.
Main Methods:
- Retrospective review of 310 CABG patients, identifying 20 with ischemic cardiomyopathy (ejection fraction <0.30).
- Measurement of preoperative and postoperative ejection fraction and LVESVI using biplane cineventriculography.
- Group division based on preoperative LVESVI: <100 mL/m2 (Group A) and >100 mL/m2 (Group B).
Main Results:
- Group A showed a significant increase in ejection fraction (0.25 to 0.40) and decrease in LVESVI (83.2 to 61.7 mL/m2) post-CABG.
- Group B demonstrated no significant change in ejection fraction or LVESVI.
- Four patients in Group B required rehospitalization for congestive heart failure.
Conclusions:
- Patients with preoperative LVESVI <100 mL/m2 experience significant improvement in ejection fraction after CABG.
- Preoperative LVESVI is a valuable predictor of postoperative ventricular function and patient outcomes in ischemic cardiomyopathy.
- LVESVI stratification can aid in surgical decision-making for patients with reduced ejection fraction.
Background:
We investigated the usefulness of the preoperative left ventricular end-systolic volume index (LVESVI) as a predictor of postoperative ventricular function.
Methods:
We retrospectively reviewed the records of 310 patients who underwent coronary artery bypass grafting and identified 20 patients with ischemic cardiomyopathy with a preoperative ejection fraction less than 0.30. We determined the preoperative and postoperative ejection fraction, LVESVI, and left ventricular enddiastolic volume index using biplane left cineventriculography. Patients were divided into groups depending on whether their preoperative LVESVI was less than 100 mL/m2 (group A, n = 10) or greater than 100 mL/m2 (group B, n = 10).
Results:
The mean ejection fraction increased significantly after coronary artery bypass grafting in group A from 0.25 +/- 0.05 to 0.40 +/- 0.09 (p < 0.01), but did not change significantly in group B (0.26 +/- 0.05 versus 0.23 +/- 0.06). The mean LVESVI decreased significantly in group A from 83.2 +/- 13.7 to 61.7 +/- 20.4 mL/m2 after operation (p < 0.05), but did not change significantly in group B (124.7 +/- 21.0 versus 121.5 +/- 37.6 mL/m2). In group B, 4 patients had signs of congestive heart failure during the follow-up period and had to be rehospitalized.
Conclusions:
The mean ejection fraction improved significantly after coronary artery bypass grafting in patients with a preoperative LVESVI less than 100 mL/m2, despite the presence of a global left ventricular ejection fraction less than 0.30. Our results suggest that the preoperative LVESVI predicts the postoperative status and left ventricular function in patients with ischemic cardiomyopathy.
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