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4-(Acetylamino)-3-hydroxy-5-nitrobenzoic acid
M J Jedrzejas1, M Luo, S Singh
1Department of Microbiology, University of Alabama at Birmingham 35294, USA.
Acta Crystallographica. Section C, Crystal Structure Communications
|September 15, 1995
Abstract:
The 4-(acetylamino)-3-hydroxy-5-nitrobenzoic acid molecule, C9H8N2O6, a designed inhibitor for the influenza virus neuraminidase protein, crystallizes as hydrogen-bonded dimers. The dihedral angles of the substituent groups with respect to the planar phenyl moiety are 5.0 (3) degrees for the carboxyl group, 45.0 (2) degrees for the nitro group and 37.3 (1) degrees for the acetylamino substituent. The crystal structure is stabilized by intermolecular hydrogen bonding.