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Antibacterial activity of flavanostilbenes against methicillin-resistant Staphylococcus aureus
M Sato1, H Tsuchiya, T Miyazaki
1Department of Oral Microbiology, Asahi University School of Dentistry, Gifu, Japan.
Letters in Applied Microbiology
|October 1, 1995
Abstract:
Three phytochemical compounds (alopecurone A-C), flavanostilbenes which are produced by condensation between a hydroxyflavanone and a hydroxystilbene, were isolated as major components from the root of Sophora alopecuroides. They uniformly inhibited the growth of 21 strains of methicillin-resistant Staphylococcus aureus with minimum inhibitory concentrations of 3.13-6.25 micrograms ml-1.