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[Blood component transfusion in Croatia]
Summary
Blood component therapy offers better patient outcomes, safety, and economy. To meet demand, Croatia needs more blood donations and increased use of blood component therapy.
Area of Science:
- Hematology
- Transfusion Medicine
Context:
- Blood component therapy is globally accepted for its efficacy, safety, and cost-effectiveness.
- In SRH (Socialist Republic of Croatia), adoption of blood component therapy lags behind global trends, evidenced by slow production and utilization of blood derivatives over a five-year period (1974-1978).
- Despite an increase in blood donations to 27 per 1,000 inhabitants, this figure remains significantly below the optimal range of 40-60 donations per 1,000 inhabitants.
Purpose:
- To assess the production and utilization of blood derivatives in SRH between 1974 and 1978.
- To evaluate the sufficiency of current blood derivative quantities to meet healthcare demands.
- To identify strategies for increasing blood plasma availability and optimizing blood component therapy implementation.
Summary:
- Production of albumin, immunoglobulins, and Factor VIII saw substantial increases (5-10 fold) during 1974-1978.
- In 1978, per 1,000 inhabitants, 2.1 L of plasma were fractionated, with 53g albumin and 23ml immunoglobulins used, alongside 6,200 units for hemophiliacs.
- These quantities were insufficient to meet the healthcare service needs in SRH.
Impact:
- The study highlights a critical shortage of essential blood derivatives in SRH.
- Recommendations include increasing blood donation rates, raising average donation volume to 450ml, expanding plasmapheresis, and scaling up blood component therapy.
- Achieving 10-12 L of plasma for fractionation per 1,000 inhabitants is crucial for securing optimal derivative quantities.