Related Experiment Videos
[Acute pancreatitis associated with hepatotoxicity induced by amoxicillin-clavulanic acid]
C Galindo1, J Buenestado, J M Reñé
1Sección Digestivo, Hospital Arnau de Vilanova, Facultad de Medicina, Lleida.
Revista Espanola De Enfermedades Digestivas
|August 1, 1995
Abstract:
A 25-year old man suffered from acute pancreatitis and cholestatic acute hepatitis simultaneously after 4 weeks of an antibiotic treatment withdrawal (amoxicillin plus clavulanic acid) which was given for pharyngitis. Other potential etiological causes of both acute pancreatitis and liver disease, were excluded. The causal relationship between amoxicillin plus clavulanic acid and cholestatic hepatitis is well know, but no data has been reported regarding acute pancreatitis. The medical literature is reviewed and the mechanisms of toxicity are discussed.