Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Flow characteristics of aortic cannulae

D D Muehrcke1, J F Cornhill, J D Thomas

  • 1Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, Ohio 44194, USA.

Journal of Cardiac Surgery
|July 1, 1995
PubMed
Summary

A novel arterial cannula design significantly reduces blood flow exit force and velocity, potentially decreasing atheroemboli complications after open heart surgery. This innovation aims to improve patient outcomes by mitigating the "sandblasting" effect on the aorta.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Internal mammary artery grafting: The gold standard of coronary revascularization for 40 years and counting.

The Journal of thoracic and cardiovascular surgery·2026
Same author

Safety and efficacy of intraarterial thrombolysis for perioperative stroke after cardiac operation.

The Annals of thoracic surgery·2002
Same author

Modified quadrangular resection for mitral valve repair.

The Annals of thoracic surgery·2002
Same author

Is repair preferable to replacement for ischemic mitral regurgitation?

The Journal of thoracic and cardiovascular surgery·2001
Same author

Mechanical properties of myxomatous mitral valves.

The Journal of thoracic and cardiovascular surgery·2001
Same author

Age and valve size effect on the long-term durability of the Carpentier-Edwards aortic pericardial bioprosthesis.

The Annals of thoracic surgery·2001

Area of Science:

  • Cardiovascular Surgery
  • Biomedical Engineering
  • Fluid Dynamics

Background:

  • Atheroembolism from the ascending aorta is an emerging complication after open heart surgery.
  • The "sandblasting" effect of blood flow from arterial cannulae contributes to atheroemboli formation.
  • Existing arterial cannulae may pose a risk for atheroembolic events.

Purpose of the Study:

  • To design and evaluate a novel arterial cannula engineered to minimize blood flow exit force and velocity.
  • To compare the fluid dynamics of the new cannula against five commonly used arterial cannulae.
  • To assess the potential of the new cannula to reduce atheroembolism after open heart surgery.

Main Methods:

  • A new arterial cannula with a closed tip and internal cone diffusing flow through side holes was designed.

Related Experiment Videos

  • Fluid dynamics, including exit force and peak velocity, were tested against five established cannulae (Sarns High-Flow, DLP, RMI, Bard, Argyle) of 8.0-mm external diameter.
  • Hemolysis rates were compared across all tested cannulae.

    • Main Results:

    • The new "Soft Flow" cannula demonstrated significantly lower exit force compared to all tested cannulae (p < 0.05).
    • Peak flow velocity was significantly reduced with the Soft Flow cannula compared to DLP, RMI, Bard, and Argyle cannulae (p < 0.01).
    • Pressure drop and internal tip diameter were similar across all cannulae; hemolysis rates were comparable.

    Conclusions:

    • The novel Soft Flow arterial cannula effectively reduces exit force and flow velocity without increasing hemolysis.
    • This design innovation holds promise for mitigating the incidence of atheroemboli and associated complications following open heart surgery.
    • Further clinical evaluation is warranted to confirm the benefits of this new cannula design in reducing atheroembolic events.