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Quality assurance in weighing

A S Kenyon1, J C Black, T P Layloff

  • 1U.S. Food and Drug Administration, Division of Drug Analysis, St. Louis, MO 63101-2045, USA.

Journal of AOAC International
|July 1, 1995
PubMed
Summary
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Accurate weighing is crucial in laboratory analysis. A common error, drift, was identified and a procedure developed to reduce it, enhancing overall quality assurance in laboratory operations.

Area of Science:

  • Analytical Chemistry
  • Laboratory Science

Background:

  • Weighing is a fundamental and frequently performed step in analytical procedures.
  • Balances are essential laboratory equipment for all analyses.
  • Weighing errors can significantly impact final analytical results and are often undetected.

Purpose of the Study:

  • To investigate the source of weighing errors in a laboratory setting.
  • To develop a procedure for reducing weighing drift.
  • To improve the accuracy of weighings and enhance quality assurance.

Main Methods:

  • Identified weighing drift as the principal source of error.
  • Conducted an investigation into the causes of drift.
  • Developed and implemented a procedure to minimize drift.

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Main Results:

  • The investigation successfully identified the cause of weighing errors as drift.
  • A new procedure was established to effectively reduce drift.
  • Implementation of the procedure led to consistently accurate weighings.

Conclusions:

  • Addressing weighing drift is critical for reliable analytical results.
  • The developed procedure significantly improved weighing accuracy.
  • Enhanced weighing accuracy contributed to improved overall quality assurance in laboratory operations.