Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Endothelial cell transplantation

S K Williams1

  • 1Department of Surgery, University of Arizona Health Sciences Center, Tucson 85724, USA.

Cell Transplantation
|July 1, 1995
PubMed
Summary
This summary is machine-generated.

Transplanting endothelial cells onto vascular grafts improves their function. Research focuses on cell sources, polymer interactions, healing, and using cells for genetic engineering to enhance graft performance.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Uncontrolled blood pressure and risk of sleep apnea among blacks: findings from the Metabolic Syndrome Outcome (MetSO) study.

Journal of human hypertension·2015
Same author

Survey of management of common iliac artery aneurysms by members of the Vascular Society of Great Britain and Ireland.

Annals of the Royal College of Surgeons of England·2014
Same author

Effects of packaging systems and fat concentrations on microbiology, sensory and physical properties of ground beef stored at 4±1°C for 25 days.

Meat science·2014
Same author

Quantification of hepatic FOXP3+ T-lymphocytes in HIV/hepatitis C coinfection.

Journal of viral hepatitis·2014
Same author

Prenatal and gestational cocaine exposure: Effects on the oxytocin system and social behavior with implications for addiction.

Pharmacology, biochemistry, and behavior·2013
Same author

Generation of a functional liver tissue mimic using adipose stromal vascular fraction cell-derived vasculatures.

Scientific reports·2013
Same journal

Transplantation of human umbilical mesenchymal stromal cells attenuates heart failure progression in a rat model.

Cell transplantation·2026
Same journal

Three-dimensionally printed mesoporous bioactive glass for craniomaxillofacial bone regeneration: Material evolution, functional mechanisms, and clinical translation.

Cell transplantation·2026
Same journal

Hotspots and trends in stem cell therapy for ligament injuries: A bibliometric analysis (2001-2025).

Cell transplantation·2026
Same journal

Amniotic epithelial cells enhance islet engraftment by suppressing early inflammation in intraportal transplantation.

Cell transplantation·2026
Same journal

Cdc42-Modified BMSC-Derived exosomes promote acellular nerve allografts to bridge sciatic nerve defects.

Cell transplantation·2026
Same journal

Organ-on-a-chip as a next-generation tool in drug development: A bibliometric and patent analysis.

Cell transplantation·2026
See all related articles

Area of Science:

  • Biomedical Engineering
  • Vascular Biology
  • Cell Biology

Background:

  • Endothelial cells are crucial for vascular homeostasis and function.
  • Small diameter polymeric vascular grafts often fail due to lack of a functional lumenal endothelium.
  • Endothelial cell transplantation is a promising strategy to improve vascular graft performance.

Purpose of the Study:

  • To explore the potential of endothelial cell transplantation for improving vascular graft function.
  • To investigate critical issues related to endothelial cell transplantation onto polymeric grafts.

Main Methods:

  • Review of existing research on endothelial cell transplantation for vascular grafts.
  • Analysis of challenges including cell source, material interactions, and healing processes.

Related Experiment Videos

Main Results:

  • Endothelial cell transplantation shows potential for enhancing vascular graft function.
  • Key challenges identified include sourcing cells, understanding endothelium-polymer interactions, and optimizing graft healing.
  • Future directions involve utilizing endothelial cells for genetic engineering applications.

Conclusions:

  • Endothelial cell transplantation is a vital strategy for improving vascular graft outcomes.
  • Addressing challenges in cell sourcing, material compatibility, and healing is essential for clinical success.
  • Genetic engineering of endothelial cells offers future therapeutic possibilities for vascular regeneration.