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Updated: Aug 6, 2026

Establishment of a Clinic-based Biorepository
Published on: May 29, 2017
Intraoperative radiation therapy and Mohs micrographic surgery on an outpatient basis
1Department of Otolaryngology, Arthur G. James Cancer Hospital and Research Institute, Ohio State University, Columbus 43210, USA.
Background:
Intraoperative radiation therapy (IORT) is used to deliver therapeutic doses of radiation to a surgically exposed tumor or tumor bed while minimizing the radiation dose to adjacent normal tissue. It is traditionally given with the patient under general anesthesia.
Objective:
To report a case of a recurrent squamous cell carcinoma treated with Mohs micrographic surgery and IORT on an outpatient basis.
Methods:
Mohs surgery was used to clear the tumor in all fields except for the area of the spinal accessory nerve, which was preserved. IORT was then delivered to the area of nerve with possible residual tumor.
Results:
The patient remains clinically tumor free 42 months posttreatment. There were no complications.
Conclusion:
Intraoperative radiation therapy can be effectively used in the outpatient setting as an adjunctive therapy after Mohs micrographic surgery.

