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The influence of some cations on PAF-induced gastric mucosal damage in rats
M Nechifor1, B I Neughebauer, M Adomnicĭ
1Department of Pharmacology, Univ. Med. Pharm. Iaşi, Romănia.
Abstract:
We investigated the influences of Li2CO3 1 g/kg i.p., MgSO4 1 g/kg i.p. and Zinc acexamate 100 mg/kg p.o. on gastric lesions induced by Platelet Activating Factor (PAF), 2 micrograms/kg i.v. in rats. Our data show that, Li+ has no a significant influence, while Mg2+ decrease significantly the PAF induced gastric lesions.