Three more cyclotheonamides, C, D, and E, potent thrombin inhibitors from the marine sponge Theonella swinhoei
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Y Nakao1, S Matsunaga, N Fusetani
1Laboratory of Marine Biochemistry, Faculty of Agriculture, University of Tokyo, Japan.
Bioorganic & Medicinal Chemistry
|August 1, 1995
Abstract:
Three new thrombin and trypsin inhibitors, cyclotheonamides C (3), D (4), and E (8) were isolated from the marine sponge Theonella swinhoei. Their structures were determined by spectral and chemical methods.