Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Design of an object-oriented database for reverse genetics

K J Kochut1, J Arnold, J A Miller

  • 1Department of Computer Science, University of Georgia, Athens, USA.

Proceedings. International Conference on Intelligent Systems for Molecular Biology
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Control of Ixodes scapularis (Acari: Ixodidae) with topical self-application of permethrin by white-tailed deer inhabiting NASA, Beltsville, Maryland.

Journal of vector ecology : journal of the Society for Vector Ecology·2003
Same author

Sickle cell crisis in the adult: chest radiographic findings and comparison with pediatric sickle cell disease.

Journal of the National Medical Association·2003
Same author

Pharmacokinetics of ivermectin in llamas (Lama glama).

The Veterinary record·2002
Same author

Urinary incontinence: a classification system and treatment protocols for the primary care provider.

Journal of the American Academy of Nurse Practitioners·2002
Same author

Infrared frequency-modulation probing of product formation in alkyl + O2 reactions. Part IV. Reactions of propyl and butyl radicals with O2.

Faraday discussions·2002
Same author

A direct transition state theory based analysis of the branching in NH2 + NO.

Faraday discussions·2002
Same journal

Proceedings of the 8th International Conference on Intelligent Systems for Molecular Biology (ISMB 2000). San Diego, California, USA. August 19-23, 2000.

Proceedings. International Conference on Intelligent Systems for Molecular Biology·2001
Same journal

Analysis of gene expression data with pathway scores.

Proceedings. International Conference on Intelligent Systems for Molecular Biology·2000
Same journal

Towards a complete map of the protein space based on a unified sequence and structure analysis of all known proteins.

Proceedings. International Conference on Intelligent Systems for Molecular Biology·2000
Same journal

Mining for putative regulatory elements in the yeast genome using gene expression data.

Proceedings. International Conference on Intelligent Systems for Molecular Biology·2000
Same journal

A multiple alignment algorithm for metabolic pathway analysis using enzyme hierarchy.

Proceedings. International Conference on Intelligent Systems for Molecular Biology·2000
Same journal

Sequence database search using jumping alignments.

Proceedings. International Conference on Intelligent Systems for Molecular Biology·2000
See all related articles

Researchers designed an object-oriented database for reverse genetics, enabling identification of biochemical functions for DNA fragments. This tool aids fungal genetics research by linking genetic data to biological pathways and functions.

Area of Science:

  • Bioinformatics
  • Genetics
  • Computational Biology

Background:

  • Reverse genetics requires efficient data management and integration.
  • Existing databases lack comprehensive tools for linking genetic data to functional information.
  • Fungal genetics research benefits from integrated systems for genome analysis.

Purpose of the Study:

  • To design an object-oriented database system tailored for reverse genetics applications.
  • To create an electronic tool for identifying the biochemical function of DNA fragments in fungi.
  • To facilitate research in fungal development, metabolism, and evolution.

Main Methods:

  • Development of an object-oriented database architecture.
  • Encapsulation of genetic and physical map data.

Related Experiment Videos

  • Implementation of methods for linking to external databases (GenBank, PIR, MedLine).

    • Main Results:

    • A database system designed to integrate genetic mapping data and functional analysis methods.
    • Enables electronic reverse genetics for identifying gene functions.
    • Provides a framework for studying specific fungal pathways and processes.

    Conclusions:

    • The proposed database system offers a novel electronic tool for the fungal genetics community.
    • Facilitates the identification of biochemical functions for DNA fragments, advancing reverse genetics.
    • Supports genome mapping initiatives for filamentous fungi like Aspergillus nidulans and Neurospora crassa.