Jove
Visualize
Contact Us

Related Experiment Videos

Plasticity: the mirror of experience

D N Spinelli, F E Jensen

    Science (New York, N.Y.)
    |January 5, 1979
    PubMed
    Summary

    Early avoidance training in kittens creates significant neural changes in visual and somatic cortices. These experiences powerfully shape brain development and influence how future stimuli are processed.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Regional differences in susceptibility to hypoxic-ischemic injury in the preterm brain: exploring the spectrum from white matter loss to selective grey matter injury in a rat model.

    Neurology research international·2012
    Same author

    Minocycline treatment following hypoxic/ischaemic injury attenuates white matter injury in a rodent model of periventricular leucomalacia.

    Neuropathology and applied neurobiology·2008
    Same author

    Decreased glutamate receptor 2 expression and enhanced epileptogenesis in immature rat hippocampus after perinatal hypoxia-induced seizures.

    The Journal of neuroscience : the official journal of the Society for Neuroscience·2001
    Same author

    Topiramate blocks perinatal hypoxia-induced seizures in rat pups.

    Annals of neurology·2001
    Same author

    Maturational aspects of epilepsy mechanisms and consequences for the immature brain.

    Epilepsia·2001
    Same author

    Developmental seizures induced by common early-life insults: short- and long-term effects on seizure susceptibility.

    Mental retardation and developmental disabilities research reviews·2000
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies

    Area of Science:

    • Neuroscience
    • Developmental Neuroscience
    • Sensory Processing

    Background:

    • Early life experiences significantly influence neural development.
    • The impact of specific training paradigms on cortical plasticity is a key area of research.

    Purpose of the Study:

    • To investigate the long-term neural effects of simple avoidance training during early development in kittens.
    • To determine if early sensory experiences can induce unique cellular properties in the visual and somatic cortices.

    Main Methods:

    • Kittens underwent a simple avoidance training procedure during early development.
    • Neural activity and cellular properties in visual and somatic cortices were analyzed post-training.

    Main Results:

    • Massive neural traces were observed in the visual and somatic cortices following avoidance training.
    • A majority of cells in these areas showed response preferences for training-specific stimuli.
    • Some cells exhibited novel properties not seen in untrained control animals.

    Conclusions:

    • Early life experiences, even simple ones, exert a powerful influence on brain development.
    • Specific early training can profoundly alter cortical organization and sensory processing.
    • These early-induced changes affect how subsequent environmental stimuli are perceived and processed.

    Related Experiment Videos