Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Screening for congenital hypothyroidism in Turkey

N Yordam1, A S Calikoğlu, S Hatun

  • 1Hacettepe University, Department of Paediatric Endocrinology, Ankara, Turkey.

European Journal of Pediatrics
|August 1, 1995
PubMed
Summary

Congenital hypothyroidism (CH) incidence in Turkey is high at 1:2736. This pilot study highlights the need for a nationwide newborn screening program to detect CH early and initiate timely treatment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Field scale evaluation of agronomic and malting quality traits in hybrid barley.

BMC plant biology·2026
Same author

Pharmacokinetics, plasma protein binding and bioavailability of Ketoprofen in Pekin ducks after different routes of administration.

British poultry science·2025
Same author

Change in intraocular lens power calculation results after ptosis surgery.

Journal francais d'ophtalmologie·2025
Same author

Correction: Corneal sensitivity and subjective complaints of ocular pain in patients with fibromyalgia.

Eye (London, England)·2024
Same author

Diazoxide-Induced Neutropenia and Long-Term Follow-up in a Patient with Hyperinsulinemia-Hyperammonemia due to GLUD1 Mutation.

Acta endocrinologica (Bucharest, Romania : 2005)·2022
Same author

The ameliorative effects of <i>Nigella sativa</i>, thymoquinone, and bentonite against aflatoxicosis in broilers via AFAR and Nrf2 signalling pathways, and down-regulation of caspase-3.

British poultry science·2021

Area of Science:

  • Endocrinology
  • Pediatrics
  • Public Health

Background:

  • Congenital hypothyroidism (CH) is a common endocrine disorder in newborns.
  • Early detection and treatment are crucial to prevent irreversible intellectual disability.
  • The incidence of CH varies globally, necessitating regional data collection.

Purpose of the Study:

  • To determine the incidence of CH in Turkey.
  • To establish a model for a nationwide CH screening program.
  • To assess the feasibility of integrating CH screening with existing newborn screening initiatives.

Main Methods:

  • A pilot study screened 30,097 newborns in Turkey between December 1991 and December 1992.
  • Thyroid-stimulating hormone (TSH) levels were measured in capillary blood on days 3-5 of life.

Related Experiment Videos

  • Screening was conducted in collaboration with the national phenylketonuria screening program.

    • Main Results:

    • Eleven cases of primary CH were identified, yielding an incidence of 1:2736.
    • The recall rate for further testing was 2.3%.
    • Replacement therapy with L-thyroxine was initiated, with a median age of 23 days.

    Conclusions:

    • The incidence of CH in Turkey is significantly higher than in many other countries.
    • Potential contributing factors include iodine deficiency and/or dyshormonogenesis.
    • The findings strongly support the implementation of a nationwide CH screening program in Turkey.