Related Experiment Videos
Frequency of various congenital heart diseases: analysis of 3790 consecutively catheterised patients
V Suresh1, A S Rao, S T Yavagal
1Department of Cardiology, Sri Jayadeva Institute of Cardiology, Bangalore.
Insights
This study analyzed congenital heart disease (CHD) in 3790 patients, finding higher pulmonary hypertension rates and ethnic variations compared to Western data. Corrective surgery was performed in 63% of cases.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Clinical Research
Background:
- Congenital heart disease (CHD) presents diverse clinical manifestations and epidemiological patterns globally.
- Understanding regional variations in CHD incidence is crucial for targeted healthcare and research.
- Previous studies suggest ethnic and geographic differences in the prevalence of specific CHD types.
Purpose of the Study:
- To retrospectively analyze the incidence and patterns of congenital heart disease (CHD) in a South Asian population.
- To compare the findings with existing data from Asian and Western countries.
- To investigate the prevalence of pulmonary arterial hypertension (PAH) in CHD patients and compare it with Western literature.
Main Methods:
- Retrospective analysis of hemodynamic and angiographic data from 3790 consecutive patients with CHD.
- Data collected from Sri Jayadeva Institute of Cardiology, Bangalore, between April 1981 and April 1994.
- Comparison of CHD incidence and specific lesion prevalence with international studies.
Main Results:
- CHD was diagnosed in 54.3% (3790/6985) of patients undergoing hemodynamic studies.
- Shunt lesions (atrial septal defect, ventricular septal defect, patent ductus arteriosus) constituted approximately 63% of CHD cases.
- Pulmonary arterial hypertension (PAH) was observed in 15% (367) of CHD patients, a higher incidence than reported in Western literature.
- Congenital aortic stenosis and coarctation of the aorta were less common than in Western countries.
- Tetralogy of Fallot was less common than in Eastern countries.
- Corrective surgery was performed in approximately 63% of the CHD cases.
Conclusions:
- Significant ethnic differences exist in the incidence of various congenital heart diseases.
- The prevalence of pulmonary arterial hypertension in congenital heart disease patients in this cohort is notably higher than in Western populations.
- Findings underscore the importance of regional data for understanding CHD epidemiology and guiding clinical management.
Abstract:
A retrospective analysis of 3790 consecutive patients with congenital heart disease (CHD) who underwent haemodynamic and angiographic studies at Sri Jayadeva Institute of Cardiology, Bangalore, from April 1981 to April 1994 has been done. The incidence of various CHD has been compared with that in other series from Asian and Western countries. Out of 6985 patients who underwent haemodynamic studies, 3790 had CHD (54.3%). Approximately 63 percent (2386) of these cases had shunt lesions like atrial septal defect (ASD), ventricular septal defect (VSD) and patent ductus arteriosus (PDA). Among them, 15 percent (367) had pulmonary arterial hypertension of various grades. The overall incidence of pulmonary arterial hypertension is higher than that reported in the Western literature. Corrective surgery was done in approximately 63 percent of cases. Ethnic differences in the incidence of CHD were found in this study when compared to the Eastern and Western literature. Congenital aortic stenosis and coarctation of aorta were less common compared to Western countries and Tetralogy of Fallot was less common compared to Eastern countries.