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Distribution of Body Mass Index in Indian patients with coronary artery disease
1Department of Cardiology, Christian Medical College Hospital, Vellore.
Insights
Indian patients with coronary artery disease (CAD) often have a low Body Mass Index (BMI), challenging typical obesity assumptions. This study found that CAD can occur even with a BMI below overweight thresholds.
Area of Science:
- Cardiology
- Public Health
- Anthropometry
Background:
- Coronary artery disease (CAD) is a significant health concern globally.
- Obesity is a known risk factor for CAD, but its prevalence in Indian populations with CAD requires specific investigation.
- Understanding the Body Mass Index (BMI) distribution in Indian CAD patients is crucial for risk stratification and prevention strategies.
Purpose of the Study:
- To determine the prevalence of overweight and obesity among Indian patients diagnosed with coronary artery disease (CAD).
- To analyze the relationship between Body Mass Index (BMI) and the severity of CAD in Indian patients.
- To explore correlations between BMI, traditional cardiovascular risk factors, and demographic factors in this population.
Main Methods:
- A cross-sectional analysis was conducted on computerized data of 1078 Indian patients with angiographically proven CAD.
- Body Mass Index (BMI) was calculated using height and weight data, with overweight defined as BMI > 27 kg/m2 and obesity as BMI > 30 kg/m2.
- Statistical analysis examined BMI distribution across different CAD severities and in relation to risk factors like smoking, diabetes, hypertension, family history, occupation, and lipid profiles.
Main Results:
- Only 8.2% of Indian CAD patients were overweight, and 2.2% were obese, indicating a significant proportion have CAD with normal or low BMI.
- Coronary artery disease was observed in individuals with BMIs as low as 15 kg/m2.
- No significant difference in BMI was found between patients with and without smoking, diabetes, or hypertension, but BMI was higher in those with a positive family history (p < 0.01).
- BMI was higher in businessmen and executives, though not reaching overweight or obese categories, and showed no correlation with lipid fractions.
Conclusions:
- Angiographically proven coronary artery disease in Indian patients can be present even with a low Body Mass Index (BMI).
- The findings challenge the universal applicability of BMI thresholds for overweight and obesity in the context of CAD risk assessment in Indian populations.
- Further research is needed to understand the specific etiological factors contributing to CAD in lean or normal-weight Indian individuals.
Abstract:
To study the distribution of overweight and obesity among Indian patients with coronary artery disease (CAD), a cross-sectional analysis of computerized data on patients, proved to have CAD by selected coronary arteriography, was carried out. There were 1078 patients, with 1052 males (mean age +/- SD:50 +/- 7.5) and 26 females (mean age +/- SD:47.7 +/- 8). Of these, 22 percent had single vessel disease, 38 percent two vessel and 40 percent three vessel disease. The Body Mass Index (BMI) was calculated from the height and weight data. BMI over 27 kg/m2 was defined as overweight and that over 30 kg/m2 as obese. Data analysis revealed that only 8.2 percent of patients with CAD were overweight, of whom 2.2 percent were obese. CAD was seen in Indians with BMI from 15 kg/m2 onwards. The BMI in the risk factor groups of smoking, diabetes and hypertension was not different when compared to those without the risk factors. However, the BMI was higher in those with a positive family history (p < 0.01). BMI was higher in the businessmen and executives but did not qualify for overweight or obesity group. BMI did not correlate with the various lipid fractions studied. It is concluded, that in Indian patients, angiographically proved coronary artery disease can be seen with low BMI.
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