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Nevus sebaceus: clinical outcome and considerations for prophylactic excision
K Chun1, M Vázquez, J L Sánchez
1Department of Dermatology, University of Puerto Rico School of Medicine, San Juan, Puerto Rico.
International Journal of Dermatology
|August 1, 1995
Summary
Prophylactic surgical excision of nevus sebaceus is often recommended, but this study found benign neoplasms infrequently. Excision is only warranted for suspected neoplasms or cosmetic reasons.
Area of Science:
- Dermatology
- Dermatopathology
- Surgical Pathology
Background:
- Nevus sebaceus is a skin hamartoma with potential for neoplasm development.
- Prophylactic excision is commonly advocated before puberty.
- Authors questioned the frequency and aggressiveness of neoplasms in nevus sebaceus.
Purpose of the Study:
- To investigate the clinical outcome and histopathologic findings of excised nevus sebaceus.
- To evaluate the necessity of prophylactic surgical excision.
Main Methods:
- Retrospective review of 225 nevus sebaceus cases (175 patients) from 1987-1992.
- Histopathological analysis and clinical record review.
- Exclusion of 10 patient specimens.
Main Results:
- Nine benign neoplasms (5.4%) identified in 165 patients.
- Neoplasms included trichoblastomas, syringocystadenoma papilliferum, and aprocrine cystadenoma.
- No malignant neoplasms were detected; most excisions were prophylactic or cosmetic.
Conclusions:
- Prophylactic excision of all nevus sebaceus may not be necessary.
- Excision should be reserved for clinically suspected neoplasms or cosmetic indications.
- Further prospective studies are recommended to confirm these findings.