Related Experiment Videos
[Spherulocytosis (myospherulosis) of the paranasal sinuses]
G S Godbersen1, J Kleeberg, J Lüttges
1Klinik für Hals-, Nasen-, Ohrenheilkunde, Universität Kiel.
Abstract:
Spherulocytosis (myospherulosis is a disease resulting from the physical emulsion phenomenon between lipid-containing materials and blood. It can be caused by the application of lipid-based ointments with or without antibiotics to wounds. This "foreign-body" reaction appears as a granulation tissue that will cause symptomatic when developing under closed wounds or in such cavities as the middle ear or paranasal sinuses. Poor healing after paranasal sinus surgery may be due to spherulocytosis. This occurred in several cases managed at the University Hospital in Kiel as the result of postoperative nasal packs sensitizing sinus mucosa. These experiences led the authors to conclude the nasal ointment packs should be avoided in paranasal sinus surgery.
Insights
Spherulocytosis, a condition caused by lipid emulsions in wounds, can impede healing, particularly after paranasal sinus surgery. Avoidance of lipid-based nasal packs post-surgery is recommended to prevent this foreign-body reaction.
Area of Science:
- Medical Science
- Pathology
Background:
- Spherulocytosis (myospherulosis) arises from the interaction of lipid-based materials with blood.
- It is often associated with the application of lipid-containing ointments or antibiotic preparations to wounds.
Observation:
- This condition triggers a foreign-body reaction, manifesting as granulation tissue.
- Symptomatic development occurs in closed wounds or cavities like the middle ear and paranasal sinuses.
Findings:
- Poor healing following paranasal sinus surgery may be attributed to spherulocytosis.
- Cases at University Hospital in Kiel indicated postoperative nasal packs sensitized sinus mucosa, leading to this complication.
Implications:
- The findings suggest that nasal ointment packs should be avoided in paranasal sinus surgery.
- This recommendation aims to prevent spherulocytosis and improve surgical outcomes.