Related Experiment Video
Updated: Aug 11, 2026

Autonomously Bioluminescent Mammalian Cells for Continuous and Real-time Monitoring of Cytotoxicity
Published on: October 28, 2013
Quantitation of antibiotic effects on bacteria by bioluminescence, viable counting and quantal analysis
L Sörén1, M Nilsson, L E Nilsson
1Department of Clinical Microbiology, University Hospital, Linköping, Sweden.
Abstract:
Discrepant results are obtained when antibiotic-induced bacterial killing is quantitated by viable counting or bioluminescence assay of intracellular ATP. In this study the killing of bacteria exposed to amikacin or imipenem was quantitated by viable counting and bioluminescence assay of intracellular ATP and also by quantal analysis. The results of quantal analysis and viable counting agreed very well, whereas a much lower degree of bacterial killing was recorded by bioluminescence.
More Related Videos
09:29In Vivo Investigation of Antimicrobial Blue Light Therapy for Multidrug-resistant Acinetobacter baumannii Burn Infections Using Bioluminescence Imaging
Published on: April 28, 2017
06:18A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials
Published on: March 3, 2023