Characterization of toxin-producing cyanobacteria by using an oligonucleotide probe containing a tandemly repeated heptamer
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Updated: Aug 10, 2026

Experimental Protocol for Detecting Cyanobacteria in Liquid and Solid Samples with an Antibody Microarray Chip
Published on: February 7, 2017
L Rouhiainen1, K Sivonen, W J Buikema
1Department of Applied Chemistry and Microbiology, University of Helsinki, Finland.
Abstract:
Cyanobacteria produce toxins that kill animals. The two main classes of cyanobacterial toxins are cyclic peptides that cause liver damage and alkaloids that block nerve transmission. Many toxin-producing strains from Finnish lakes were brought into axenic culture, and their toxins were characterized. Restriction fragment length polymorphism analysis, probing with a short tandemly repeated DNA sequence found at many locations in the chromosome of Anabaena sp. strain PCC 7120, distinguishes hepatotoxic Anabaena isolates from neurotoxin-producing strains and from Nostoc spp.
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