Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Microcirculation in high perfusion microangiopathy

G Belcaro1, G Laurora, M R Cesarone

  • 1Microcirculation Laboratory, G. D'Annunzio University, Chieti, UK.

The Journal of Cardiovascular Surgery
|August 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pycnogenol® Supplementation Prevents Recurrent Urinary Tract Infections/Inflammation and Interstitial Cystitis.

Evidence-based complementary and alternative medicine : eCAM·2021
Same author

Interaction study between antiplatelet agents, anticoagulants, thyroid replacement therapy and a bioavailable formulation of curcumin (Meriva®).

European review for medical and pharmacological sciences·2018
Same author

Effectiveness of a novel boswellic acids delivery form (Casperome®) in the management of grade II ankle sprains due to sport trauma - a registry study.

European review for medical and pharmacological sciences·2017
Same author

Mirtogenol® supplementation in association with dorzolamide-timolol or latanoprost improves the retinal microcirculation in asymptomatic patients with increased ocular pressure.

European review for medical and pharmacological sciences·2017
Same author

A natural pharma standard supplement formulation to control treatment-related toxicity and oxidative stress in genitourinary cancer: a preliminary study.

European review for medical and pharmacological sciences·2017
Same author

Management of Varicose Veins and Chronic Venous Insufficiency in a Comparative Registry with Nine Venoactive Products in Comparison with Stockings.

The International journal of angiology : official publication of the International College of Angiology, Inc·2017
Same journal

Pelvic venous disease and lymphatic dysfunction: evaluating the evidence for a proposed continuum.

The Journal of cardiovascular surgery·2026
Same journal

Incidence of post-dissection aneurysmal formation and need for secondary intervention after surgery for acute type A aortic dissections: a systematic review and meta-analysis of observational studies.

The Journal of cardiovascular surgery·2026
Same journal

The expertise effect: how advancing skills in frozen elephant trunk have broadened surgical indication for acute dissection.

The Journal of cardiovascular surgery·2026
Same journal

Outcomes of pulmonary embolism response teams: a systematic review.

The Journal of cardiovascular surgery·2026
Same journal

Use of large bore devices in the treatment of pulmonary embolism.

The Journal of cardiovascular surgery·2026
Same journal

Contemporary role of systemic thrombolysis in the management of acute pulmonary embolism.

The Journal of cardiovascular surgery·2026
See all related articles

This study identifies two microangiopathy types: low perfusion (LPM) and high perfusion (HPM). HPM, seen in conditions like diabetes, involves increased skin flux and edema, treatable with compression and specific drugs.

Area of Science:

  • Vascular Biology
  • Microcirculation Research
  • Medical Diagnostics

Background:

  • Microangiopathy, a complication affecting small blood vessels, presents diagnostic challenges.
  • Noninvasive techniques offer potential for characterizing microcirculatory dysfunction.

Purpose of the Study:

  • To differentiate between major types of microangiopathy using advanced noninvasive techniques.
  • To investigate the characteristics and potential treatments for high perfusion microangiopathy (HPM).

Main Methods:

  • Utilized laser-Doppler flowmetry for skin flux measurements.
  • Employed transcutaneous oxygen (PO2) and carbon dioxide (PCO2) monitoring.
  • Assessed capillary filtration rates and venoarteriolar response.

Related Experiment Videos

Main Results:

  • Defined two microangiopathy types: Low Perfusion Microangiopathy (LPM) and High Perfusion Microangiopathy (HPM).
  • Identified HPM characteristics: increased skin flux, reduced venoarteriolar response, and elevated capillary filtration leading to edema.
  • Demonstrated that elastic compression and capillary filtration-modulating drugs effectively reduced HPM symptoms.

Conclusions:

  • Noninvasive microcirculatory assessments can classify distinct microangiopathy types.
  • HPM is characterized by specific hemodynamic alterations and edema formation.
  • Targeted interventions show promise in managing HPM and associated edema.