Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Oxygen levels beneath the closed eyelid

N Efron, L G Carney

    Investigative Ophthalmology & Visual Science
    |January 1, 1979
    PubMed
    Summary

    Oxygen levels beneath closed eyelids are approximately 7.7%. This crucial finding for anterior eye oxygenation aligns with prior assumptions but also highlights atmospheric contributions from imperfect eyelid closure.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Latent autoimmune diabetes of adulthood (LADA) is associated with small fibre neuropathy.

    Diabetic medicine : a journal of the British Diabetic Association·2018
    Same author

    Standardizing corneal nerve fibre length for nerve tortuosity increases its association with measures of diabetic neuropathy.

    Diabetic medicine : a journal of the British Diabetic Association·2014
    Same author

    Oxygen permeability of hard gas permeable contact lens materials.

    Clinical & experimental optometry·2013
    Same author

    The vascular response to long-term extended contact lens wear.

    Clinical & experimental optometry·2013
    Same author

    The effects of fenestrating soft contact lenses on corneal swelling: a re-examination.

    Clinical & experimental optometry·2013
    Same author

    Retinal nerve fibre layer thinning associated with diabetic peripheral neuropathy.

    Diabetic medicine : a journal of the British Diabetic Association·2012

    Area of Science:

    • Ophthalmology
    • Corneal Physiology
    • Ocular Surface Science

    Background:

    • Understanding oxygen levels at the anterior corneal surface is vital for ocular health.
    • Previous studies assumed oxygen supply primarily from the palpebral conjunctiva.

    Purpose of the Study:

    • To quantify the oxygen concentration at the anterior corneal surface under a closed eyelid.
    • To investigate the sources of oxygen supply to the cornea during lid closure.

    Main Methods:

    • Measurement of oxygen levels at the anterior corneal surface beneath a closed eyelid.
    • Comparison of measured oxygen levels with theoretical assumptions based on palpebral conjunctiva oxygenation.

    Main Results:

    • The oxygen level at the anterior corneal surface beneath the closed eyelid was determined to be equivalent to 7.7% oxygen.
    • This measured value closely matched previous assumptions regarding oxygen levels at the palpebral conjunctiva.

    Conclusions:

    • The primary source of oxygen to the cornea under a closed eyelid is consistent with supply from the palpebral conjunctiva.
    • An imperfect palpebral aperture seal can lead to a significant additional supply of oxygen from the atmosphere.

    Related Experiment Videos