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Related Experiment Videos

Continuous ascitic recirculation in severe ovarian hyperstimulation syndrome

D H Beck1, S Massey, B L Taylor

  • 1Department of Intensive Care Medicine, Queen Alexandra Hospital, Portsmouth, UK.

Intensive Care Medicine
|July 1, 1995
PubMed
Summary

Severe ovarian hyperstimulation syndrome (OHSS) can cause life-threatening fluid buildup. Continuous ascitic recirculation (AR) safely and effectively drained fluid, rapidly improving respiratory function in a severe OHSS case.

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Area of Science:

  • Reproductive Endocrinology
  • Nephrology
  • Critical Care Medicine

Background:

  • Ovarian hyperstimulation syndrome (OHSS) is a serious complication of ovulation induction using exogenous gonadotropins.
  • Severe OHSS presents with massive ascites, hydrothorax, acute renal failure, and thromboembolism, posing significant clinical challenges.
  • Standard treatments like paracentesis and intravenous fluid therapy may be insufficient in critical cases.

Observation:

  • A case of severe OHSS with daily ascites exceeding five liters is presented.
  • Massive ascites and bilateral pleural effusions led to respiratory failure, necessitating intervention.
  • Continuous ascitic recirculation (AR) was initiated after conventional therapies failed.

Findings:

  • The 15-day AR procedure resulted in rapid and marked improvement of respiratory function.

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  • Febrile episodes occurred on three occasions during AR treatment.
  • No coagulation disturbances or adverse hemodynamic effects were observed during continuous AR.

    • Implications:

    • Continuous ascitic recirculation (AR) offers a safe and effective therapeutic option for complicated severe OHSS.
    • This approach can rapidly alleviate respiratory compromise caused by massive fluid accumulation.
    • Further investigation into AR for severe OHSS management is warranted.