Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Immunoendocrine reshaping with age

A E Panerai1, E Ottaviani

  • 1Department of Pharmacology, University of Milano, Italy.

International Reviews of Immunology
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Real-life use of ropeg-interferon α2b in polycythemia vera: patient selection and clinical outcomes.

Annals of hematology·2024
Same author

A venetoclax and azacitidine bridge-to-transplant strategy for NPM1-mutated acute myeloid leukaemia in molecular failure.

British journal of haematology·2023
Same author

Concurrent chromothripsis events in a case of TP53 depleted acute myeloid leukemia with myelodysplasia-related changes.

Cancer genetics·2019
Same author

Mutations and long-term outcome of 217 young patients with essential thrombocythemia or early primary myelofibrosis.

Leukemia·2015
Same author

Biological components in a standardized derivative of bovine colostrum.

Journal of dairy science·2013
Same author

Profiling of drug-metabolizing enzymes/transporters in CD33+ acute myeloid leukemia patients treated with Gemtuzumab-Ozogamicin and Fludarabine, Cytarabine and Idarubicin.

The pharmacogenomics journal·2012
Same journal

Leptin in metabolic-immune crosstalk: Mechanisms of T cell regulation and implications for autoimmune disease therapy.

International reviews of immunology·2026
Same journal

Metabolic alterations in the tumor microenvironment influence the anti-tumor immune function of CD8<sup>+</sup> T cells via epigenetic modifications.

International reviews of immunology·2026
Same journal

Macrophage markers and gene signature profiling reveals mesenchymal stem cells mediated immune modulation in Plasmodium berghei ANKA infection.

International reviews of immunology·2026
Same journal

Natural antigen landscape shaping intestinal Treg cells: Self, diet, and microbiota.

International reviews of immunology·2026
Same journal

Upregulation of ADAM10 reinforces CD8<sup>+</sup> T cells toward exhaustion in the TME.

International reviews of immunology·2026
Same journal

PTX3 promotes macrophage efferocytosis and inflammation resolution in granulomatous mastitis.

International reviews of immunology·2026
See all related articles

Aging impacts the endocrine, immune, and nervous systems through their complex interactions. This chapter explores how these interconnected systems influence each other during the aging process.

Area of Science:

  • Neuroendocrinology
  • Immunology
  • Gerontology

Background:

  • The endocrine, immune, and nervous systems exhibit significant interdependencies.
  • Evolutionary biology reveals a historical underappreciation of the interplay between these three systems, particularly evident in simpler organisms.
  • Aging affects all three systems, suggesting a common underlying mechanism.

Purpose of the Study:

  • To propose a novel perspective on the effects of aging by examining the interactions between the endocrine, immune, and nervous systems.
  • To highlight the interconnectedness of these systems in the context of aging.

Main Methods:

  • This chapter is a review and theoretical discussion.
  • It synthesizes existing knowledge on the neuroendocrine-immune axis.

Related Experiment Videos

  • It draws parallels from evolutionary biology.

    • Main Results:

    • The aging process is presented as a consequence of the reciprocal influences among the endocrine, immune, and nervous systems.
    • A holistic view of aging is proposed, integrating the functions of these three key physiological systems.

    Conclusions:

    • Understanding the intricate crosstalk between the endocrine, immune, and nervous systems is crucial for comprehending aging.
    • This integrated approach offers new insights into age-related physiological changes and potential interventions.