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Related Experiment Videos

Heart rate variability. Is it influenced by disturbed sinoatrial node function?

M Sosnowski1, T Petelenz

  • 1III Clinic of Cardiology, Silesian Medical School, Silesian Heart Center, Katowice, Poland.

Journal of Electrocardiology
|July 1, 1995
PubMed
Summary
This summary is machine-generated.

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Heart rate variability (HRV) analysis reveals increased beat-to-beat variability (DSCL) and variability range (VR) in patients with sinoatrial node dysfunction (SAND). These HRV metrics may help identify impaired sinus node function.

Area of Science:

  • Cardiology
  • Autonomic Nervous System Physiology

Background:

  • Heart rate variability (HRV) is a key indicator of autonomic nervous system influence on cardiac function.
  • The precise relationship between HRV and sinoatrial node function, particularly sinoatrial node dysfunction (SAND), requires further elucidation.

Purpose of the Study:

  • To investigate the utility of HRV analysis in differentiating patients with SAND from healthy controls.
  • To define the specific HRV parameters that are altered in the presence of SAND.

Main Methods:

  • HRV analysis was performed on 1-minute esophageal electrocardiographic recordings in 150 patients with diagnosed SAND and 50 healthy controls.
  • Two time-domain HRV variables, variability range (VR) and beat-to-beat variability (DSCL), were measured.
  • Subjects underwent transesophageal left atrial overdrive pacing to assess sinus node recovery.

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Main Results:

  • Patients with SAND exhibited significantly higher statistically adjusted means for DSCL (198 ± 206 ms) compared to controls (98 ± 89 ms).
  • VR was also significantly higher in patients with SAND (30.3 ± 23.3%) than in the control group (20.9 ± 121.1%).

Conclusions:

  • HRV analysis, specifically DSCL and VR, can serve as a valuable non-invasive tool for identifying sinoatrial node dysfunction.
  • Elevated DSCL and VR during short-term recordings are indicative of impaired sinus node function.