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Multiple sclerosis in Arabs in Jordan

A S al-Din1, M el-Khateeb, A Kurdi

  • 1Department of Biochemistry and Microbiology, Faculty of Medicine, Jordan University, Amman.

Journal of the Neurological Sciences
|August 1, 1995
PubMed
Summary
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Multiple sclerosis (MS) appears twice as frequent in Palestinian Arabs compared to indigenous Jordanians in Jordan. Clinical presentation and disease patterns in this study were similar to Western populations.

Area of Science:

  • Neurology
  • Epidemiology

Background:

  • Multiple sclerosis (MS) is a chronic neurological disease with varying prevalence globally.
  • Understanding MS epidemiology in diverse populations is crucial for public health and resource allocation.

Purpose of the Study:

  • To estimate the prevalence and describe the characteristics of multiple sclerosis (MS) in Jordan.
  • To compare MS occurrence between Palestinian and indigenous Jordanian populations.

Main Methods:

  • A 2-year hospital-based study (1992-1993) involving 131 multiple sclerosis patients from two referral hospitals in Jordan.
  • Prevalence estimation based on MS/ALS case ratios.
  • Subgroup analysis comparing Palestinian and Jordanian demographics and disease characteristics.

Main Results:

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  • An overall estimated MS rate of 32.1 per 100,000 population was found.
  • The disease was estimated to be twice as frequent in Palestinians (42.0/100,000) compared to indigenous Jordanians (20.0/100,000).
  • Clinical presentation, disease patterns, disability, and HLA associations were consistent with Western reports.

Conclusions:

  • Multiple sclerosis (MS) exhibits a higher estimated frequency in the Palestinian population within Jordan.
  • The clinical and epidemiological profile of MS in Jordan aligns with findings in Caucasian populations.
  • Further research into genetic and environmental factors may elucidate the observed prevalence differences.