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Clinical and ultrastructural comparison of immunohistochemically inactive and gonadotropin-producing pituitary
S Furuhata1, T Kameya, T Tsuruta
1Department of Neurosurgery, Tachikawa Kyosai Hospital, Tokyo.
Neurologia Medico-Chirurgica
|April 1, 1995
Abstract:
A clinicoendocrinological and ultrastructural comparison of immunohistochemically inactive pituitary adenomas from 14 patients and gonadotropin-positive pituitary adenomas from 26 patients was carried out. Clinicoendocrinological characteristics were similar except the male to female ratios. The immunohistochemically unstable antigenicity of gonadotropin prevents clear immunohistochemical characterization, but the difference between the two types is not absolute and may be an indication of a cell line relationship.