Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Heat pain thresholds: normative data and repeatability

D Yarnitsky1, E Sprecher, R Zaslansky

  • 1Department of Neurology, Rambam Medical Center, Haifa, Israel.

Pain
|March 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

European S2k guidelines on management of autoimmune blistering diseases in children and adolescents.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026
Same author

Body-site effect on CPM efficiency in healthy subjects: Central vs. peripheral stimulation.

Heliyon·2024
Same author

A retrospective study on the liver toxicity of oral retinoids in Chanarin-Dorfman syndrome.

Journal of the European Academy of Dermatology and Venereology : JEADV·2023
Same author

Updated S2 K guidelines for the management of bullous pemphigoid initiated by the European Academy of Dermatology and Venereology (EADV).

Journal of the European Academy of Dermatology and Venereology : JEADV·2022
Same author

Laryngeal mucous membrane pemphigoid serves as a prognostic factor for poor response to treatment with rituximab.

Clinical and experimental dermatology·2021
Same author

Evidence for cutaneous dysbiosis in dystrophic epidermolysis bullosa.

Clinical and experimental dermatology·2021
Same journal

Pain prevalence and intensity in advanced pancreatic cancer: a nationwide cohort study.

Pain·2026
Same journal

Neurobiology of the trigeminal ganglion in comparison to the dorsal root ganglion.

Pain·2026
Same journal

Peripheral kappa opioid receptors modulate cold hypersensitivity in a mouse model of chemotherapy-induced neuropathy.

Pain·2026
Same journal

Efficacy and effectiveness of melatonin for the management of musculoskeletal pain: a systematic review and meta-analysis of placebo and active controlled trials.

Pain·2026
Same journal

Predictive socio-cultural factors of pain intensity, disability, and quality of life in patients with nonspecific musculoskeletal pain: a prospective cohort study.

Pain·2026
Same journal

Reward-induced endogenous pain inhibition scales with action-outcome certainty in humans.

Pain·2026
See all related articles

This study establishes normal ranges for heat pain thresholds in healthy adults, crucial for identifying pain sensitivity variations. Repeatability coefficients are defined for reliable intra-individual comparisons over time.

Area of Science:

  • Neuroscience
  • Pain Research
  • Human Physiology

Background:

  • Accurate measurement of pain perception is essential for diagnosing and managing various pain conditions.
  • Establishing normative data for sensory thresholds is a prerequisite for identifying hyperalgesia and hypoalgesia.

Purpose of the Study:

  • To measure heat pain thresholds in a cohort of healthy subjects.
  • To establish age- and site-specific normative ranges for heat pain thresholds.
  • To determine the repeatability of heat pain threshold measurements.

Main Methods:

  • Heat pain thresholds were measured using the reaction time-inclusive method of limits on the thenar eminence and foot dorsum.
  • Tests were repeated after two weeks to assess repeatability.
  • ANOVA-based procedures were employed to define normative ranges and repeatability coefficients.

Related Experiment Videos

Main Results:

  • Normative data tables for heat pain thresholds, stratified by age, were generated for the tested body sites.
  • Repeatability coefficients were calculated, demonstrating the reliability of the measurements.
  • The established measurement range (up to 55°C) allows for the identification of both hyperalgesia and hypoalgesia.

Conclusions:

  • The study provides reliable normative data for heat pain thresholds in healthy individuals.
  • Repeatability coefficients enable robust intra-individual comparisons in longitudinal pain studies.
  • These findings support the clinical utility of heat pain threshold measurements for assessing pain sensitivity.