[Three-dimensional MR angiography of aorta with Gd-DTPA infusion and breath-holding]

Using the rapid three-dimensional gradient echo technique (FLASH 18 degrees 10/4) and Gd-DTPA administration, we performed MR angiography (MRA) of the thoracic and abdominal aorta during single or double breath-holding periods. Basic in vitro and in vivo dynamic studies showed that infusion of a relatively low concentration (74 mg Gd/ml) Gd-DTPA solution provided a strong and persistent flow signal for a considerable length of time. Eleven of 12 cases clearly demonstrated MRAs of the aorta and its main branches without respiration-induced motion artifacts, although visualization of secondary and more peripheral branches depended on their size, direction and injection-imaging timing. Although limited spatial resolution and pulsatility-induced ghost artifacts remained as problems to be solved, the ease of this method, short examination time and excellent arteriograms with no need for venous or fat suppression make it clinically acceptable and very promising.