Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[CA 125--a tumor marker?]

T Pabst1, C Ludwig

  • 1Intern-medizinische Abteilung, St. Claraspital, Basel.

Schweizerische Medizinische Wochenschrift
|June 17, 1995
PubMed
Summary
This summary is machine-generated.

The tumor marker CA 125 is valuable for monitoring ovarian cancer but not for diagnosing other abdominal conditions. Elevated CA 125 levels indicate ascites or lymphoma, not necessarily cancer.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Breast assessment using next generation handheld ultrasound device based on silicon chips: a pilot study in senology.

Archives of gynecology and obstetrics·2026
Same author

Supplementation with willow containing condensed tannins shifted nitrogen excretion from urine to faeces in yearling ewes.

Animal : an international journal of animal bioscience·2025
Same author

Discontinuation of supportive therapies in people with cystic fibrosis treated with elexacaftor/tezacaftor/ivacaftor - A patient-reported outcomes' study.

Respiratory medicine·2025
Same author

CAR T-Cell Therapies for Patients With Relapsed and Refractory Aggressive Lymphomas: Real-World Experiences From a Single Center on the Use of Radiotherapy.

Hematological oncology·2025
Same author

Characterization of Biobased Polymers at the Gas-Solid Interface─Analysis of Surface and Bulk Properties during Artificial Degradation.

Environmental science & technology·2025
Same author

Revealing the role of land-use features on macrolitter distribution in Swiss freshwaters.

Environmental pollution (Barking, Essex : 1987)·2024
Same journal

Respiratory function test in the case of temporary phrenic nerve contusion, associated with pneumoperitoneum; About the diagnostic value of laparoscopy.

Schweizerische medizinische Wochenschrift·2010
Same journal

Treatment of pulmonary tuberculosis and pleurisy by means of temporary paralysis of the diaphragm, supported by the pneumoperitoneum.

Schweizerische medizinische Wochenschrift·2010
Same journal

Boeck's disease as a tuberculous syndrome.

Schweizerische medizinische Wochenschrift·2010
Same journal

Enteral primary tubercular complexes

Schweizerische medizinische Wochenschrift·2010
Same journal

Tuberculous stenoses of the large bronchi.

Schweizerische medizinische Wochenschrift·2010
Same journal

About the enzyme action.

Schweizerische medizinische Wochenschrift·2010
See all related articles

Area of Science:

  • Oncology
  • Clinical Chemistry

Background:

  • Tumor markers like CA 125 are used for monitoring cancer treatment.
  • Their diagnostic utility in non-ovarian abdominal conditions is often limited.
  • Uncritical use can lead to misdiagnosis and unnecessary invasive procedures.

Observation:

  • Three cases highlight diagnostic challenges with CA 125 in abdominal diseases.
  • Serum CA 125 levels were analyzed in 49 patients with various abdominal conditions.
  • CA 125 was found to be an indicator of ascites and infra-diaphragmatic lymphoma involvement.

Findings:

  • CA 125 is a marker for ascites (16/16 patients) and lymphoma (11/12 patients).
  • Elevated CA 125 was observed in inflammatory abdominal diseases (5/6) and non-ovarian solid tumors (13/15).

Related Experiment Videos

  • CA 125 appears to reflect stimulated mesothelial cells rather than being a specific tumor product.

    • Implications:

    • CA 125 is confirmed as a reliable marker for ovarian cancer follow-up.
    • Its use for diagnosing general abdominal processes is not recommended due to non-specific elevation.
    • Clinical interpretation of CA 125 requires careful consideration of the clinical context.