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Bilateral sequential lung transplantation for end stage septic lung disease
1Department of Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne, UK.
Thorax
|May 1, 1995
Summary
Bilateral sequential lung transplantation (BSLT) offers comparable survival to heart-lung transplants for septic lung disease. This lung transplant method provides excellent functional results and avoids heart transplant disadvantages.
Area of Science:
- Thoracic surgery
- Transplant medicine
- Pulmonology
Background:
- Bilateral sequential lung transplantation (BSLT) is a common alternative to combined heart and lung transplantation.
- It is used for end-stage septic lung disease management.
Purpose of the Study:
- To evaluate the outcomes of BSLT for patients with septic lung disease.
- To compare BSLT survival and functional results with heart-lung transplantation.
Main Methods:
- Retrospective review of 32 consecutive patients undergoing BSLT for septic lung disease.
- Data collected from April 1988 to October 1994 at Freeman Hospital.
Main Results:
- 32 patients underwent BSLT between April 1988 and October 1994.
- 30-day survival was 85%, with 70% actuarial survival at one year.
- All surviving patients showed improved pulmonary function.
Conclusions:
- BSLT for septic lung disease provides survival rates comparable to heart-lung transplantation.
- Excellent functional outcomes are achieved with BSLT.
- Long-term results may be superior by avoiding the complications associated with heart transplantation.