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[Initial symptoms in Meniere's disease]

G Ralli1, D Celestino, M Fabbricatore

  • 1II Clinica ORL dell'Università La Sapienza di Roma.

Acta Otorhinolaryngologica Italica : Organo Ufficiale Della Societa Italiana Di Otorinolaringologia E Chirurgia Cervico-Facciale
|February 1, 1995
PubMed
Summary

Early isolated symptoms in Menière's disease are common, often cochlear, and can precede full diagnosis by years. Understanding these initial signs may improve disease management and patient outcomes.

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Area of Science:

  • Otolaryngology
  • Neurology
  • Audiology

Context:

  • Menière's disease diagnosis is often delayed until the classic triad of symptoms manifests.
  • Early disease phases offer the best chance for intervention and control.
  • The pre-diagnosis period of Menière's disease is not well understood.

Purpose:

  • To determine the prevalence of isolated symptoms before a Menière's disease diagnosis.
  • To characterize the clinical presentation of the pre-diagnosis period.
  • To explore the link between the pre-diagnosis period and the disease's progression.

Summary:

  • 63% of Menière's patients (107/170) experienced isolated symptoms before diagnosis.
  • Cochlear symptoms (71.9%) were most prevalent, followed by vestibular (22.4%) and mixed (5.6%).

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  • The pre-diagnosis period lasted 2-5 years in 41 patients, shorter for mixed symptoms.

    • Impact:

    • Patients with initial cochlear symptoms showed greater hearing deterioration post-diagnosis.
    • Early cochlear symptoms correlated with shorter vertigo attack duration.
    • Identifying early Menière's disease symptoms can inform prognosis and treatment strategies.