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Lung transplantation after previous thoracic surgical procedures
F C Detterbeck1, T M Egan, M R Mill
1Division of Cardiothoracic Surgery, University of North Carolina School of Medicine, Chapel Hill 27599-7065, USA.
The Annals of Thoracic Surgery
|July 1, 1995
Summary
Lung transplantation is safe after prior chest surgery, with no increased risk of death or major complications. However, using cardiopulmonary bypass during these procedures is linked to significantly higher morbidity and mortality.
Area of Science:
- Cardiothoracic Surgery
- Transplantation Medicine
- Pulmonary Medicine
Background:
- Examined lung transplantation outcomes in patients with prior thoracic surgical history.
- Assessed impact of previous chest tube placement on lung transplant results.
Purpose of the Study:
- To evaluate the safety and outcomes of lung transplantation in patients with previous thoracic surgical procedures.
- To identify specific factors influencing lung transplant success in this patient group.
Main Methods:
- Retrospective analysis of 69 isolated lung transplantations.
- Comparison of outcomes between patients with and without prior thoracic surgery or chest tube placement.
Main Results:
- No significant increase in morbidity or mortality observed for lung transplant recipients with prior thoracic surgery or chest tube placement.
- Increased blood product usage noted in patients with prior thoracic surgery, but not chest tube placement.
- Cardiopulmonary bypass use was associated with significantly higher rates of hospital death, complications, and longer recovery periods.
Conclusions:
- Lung transplantation is feasible in patients with previous thoracic procedures, with manageable bleeding risks but no increased major morbidity or mortality.
- Cardiopulmonary bypass significantly increases morbidity and mortality in lung transplant recipients with prior thoracic surgical history.