Related Experiment Videos
TGF-beta accelerated the osteogenic differentiation of bone marrow cells induced by collagen matrix
1Department of Biochemistry, School of Dentistry, Hokkaido University, Sapporo, Japan.
Biochemical and Biophysical Research Communications
|June 26, 1995
Abstract:
Bone marrow cells have multipotency for differentiation. Recently we found that type I collagen matrix induced the osteogenic differentiation of bone marrow cells. In this study we showed that TGF-beta enhanced the effect of collagen matrix on bone marrow cells and accelerated the osteogenic differentiation. These results imply that TGF-beta might play a crucial role in the osteogenic differentiation of bone marrow cells during embryogenesis and the repair of bone.