Clinical aspects of autosomal dominant polycystic kidney disease

Autosomal dominant polycystic kidney disease is the most common genetic disorder encountered by nephrologists. Clinically relevant areas of which the physician must be knowledgeable are reviewed, emphasizing recent genetic advances with clinical implications for patients and their families. Recent information on hypertension, infection, pain and discomfort, hepatic cysts, and intracranial aneurysms is summarized.