[The character and clinical application of glutaraldehyde cross-linked collagen artificial skin]

The glutaraldehyde cross-linked collagen artificial skin was made with the modified Burke's method. It is an ideal artificial skin in that animal tests proved that it has the effect of bacteriostasis with strong adhesiveness and good porosity, is capable of decreasing vaporization and the loss of protein and electrolyte, and without rejection reaction. Clinical use of the artificial skin in 30 patients resulted in an average healing time of 24 +/- 3 days of the eschar-excised wound covered with the artificial skin and autograft of skin seeds. It is especially effective in Pseudomonas aeruginosa infected wound and chronic ulcer.