[Observation of immune effect of 5 kinds of Denmark II lyophilized vaccines]

This paper reported five kinds of Denmark II lyophilized vaccines produced by 5 different biological production institutes. Through the double blind randomized trial in newborns after 1 year observation, the results demonstrated that all vaccines possessed the stability of heat tolerance and the 12 week tuberculin conversion rates of all group exceeded to 95%, and 1-year positive maintenance rates were in the range of 88.3%-96.1%, and the average diameter of induration was relatively large; the local reaction belonged to normal range; the swollen-lymph node rate was not high; the immune effect was satisfactory.