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Craniofacial growth in cleidocranial dysplasia--a roentgencephalometric study
1Department of Pediatric Dentistry, School of Dentistry, Faculty of Health Sciences, University of Copenhagen, Denmark.
Journal of Craniofacial Genetics and Developmental Biology
|January 1, 1995
Summary
Cleidocranial dysplasia (CCD) significantly impacts craniofacial development, affecting bone remodeling, mandibular growth, and tooth eruption. This study details these complex changes in CCD patients from childhood to adulthood.
Area of Science:
- Orthodontics
- Pediatric Dentistry
- Craniofacial Biology
Background:
- Cleidocranial dysplasia (CCD) is a genetic disorder affecting bone development.
- Understanding craniofacial growth patterns in CCD is crucial for management.
Purpose of the Study:
- To analyze craniofacial growth in cleidocranial dysplasia (CCD).
- Emphasis on bone remodeling, mandibular condylar growth, and tooth eruption.
Main Methods:
- Longitudinal study of skull radiographs from 22 CCD children.
- Analysis of bone remodeling, jaw rotation, and tooth eruption using metallic implants in 5 patients.
Main Results:
- Persistent open anterior fontanelle and underdeveloped frontal sinus.
- Reduced sella turcica growth and flexed clivus.
- Severely reduced maxillary height due to minimal nasal floor resorption.
- Vertical condylar growth leading to forward mandibular rotation.
- Negligible bone remodeling in the mandibular angle and ramus.
- Diminished anterior facial height due to low maxilla and mandibular rotation.
Conclusions:
- Cleidocranial dysplasia causes significant craniofacial abnormalities.
- Altered bone remodeling and growth patterns contribute to characteristic facial features and dental issues in CCD.