Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cancer in married couples

H M Payan

    Southern Medical Journal
    |January 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    This study found 19 married couples with cancer, suggesting environmental factors may play a role in cancer development, not just genetics. Cancers often appeared in wives before husbands.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Acute surgical abdomen and myelofibrosis.

    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc·1989
    Same author

    Mesenteric cyst-ovarian implant syndrome.

    Archives of pathology & laboratory medicine·1987
    Same author

    Fibrosarcoma mimicking breast fibromatosis.

    American journal of medical genetics. Supplement·1987
    Same author

    Granulomatous coronary arteritis.

    Archives of pathology & laboratory medicine·1984
    Same author

    Granulomatous appendicitis.

    Diseases of the colon and rectum·1981
    Same author

    Cobalt-induced epilepsy: an ultrastructural study.

    Neurological research·1979
    Same journal

    SMA's 6th Annual Physicians-in-Training Leadership Conference Abstract Presentations.

    Southern medical journal·2026
    Same journal

    Potential Impact of Lower Federal Loan Availability on Medical Education in Appalachia.

    Southern medical journal·2026
    Same journal

    Experiential Mentorship Skills Training: The Effect on Real-Life Mentoring.

    Southern medical journal·2026
    Same journal

    Social Pressure: How Early Social Context Shapes Career Interest in Medicine.

    Southern medical journal·2026
    Same journal

    Comparing Speed and Accuracy of Artificial Intelligence Large Language Models on the Orthopedic In-Training Examination.

    Southern medical journal·2026
    Same journal

    Don't Wait to Talk about Weight: A 2-Hour Interactive Curriculum Improves Medical Student Skills with Weight Management.

    Southern medical journal·2026
    See all related articles

    Area of Science:

    • Oncology
    • Epidemiology
    • Environmental Health

    Background:

    • Cancer etiology is often attributed to genetic factors.
    • Environmental influences on cancer development in couples are less understood.
    • Family history documentation frequently prioritizes genetics over shared environmental exposures.

    Purpose of the Study:

    • To investigate the occurrence of cancer in married couples within a community hospital setting.
    • To explore potential shared environmental factors contributing to cancer incidence in couples.
    • To analyze the types and timing of cancer diagnoses within affected couples.

    Main Methods:

    • Retrospective chart review of 2,512 cancer admissions over a ten-year period.
    • Identification of married couples diagnosed with cancer.

    Related Experiment Videos

  • Analysis of cancer types, histopathology, organ of origin, and temporal patterns of diagnosis.

    • Main Results:

    • Nineteen married couples were identified with cancer diagnoses.
    • Two couples shared the same cancer type from the same organ; ten pairs had identical histopathologic tumor types.
    • Cancer diagnoses occurred earlier in wives compared to husbands, despite wives being younger on average.

    Conclusions:

    • The observed clustering of similar cancer types within couples warrants further investigation into shared environmental exposures.
    • The underreporting of spousal history in family records may obscure environmental links to cancer.
    • Environmental factors, in addition to genetic predispositions, should be considered in the etiology of cancer within couples.