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Basal cell tumor in a Japanese macaque (Macaca fuscata)
T Yanai1, S Wakabayashi, T Masegi
1Department of Veterinary Pathology, Faculty of Agriculture, Gifu University, Japan.
Veterinary Pathology
|May 1, 1995
Summary
A rare basal cell tumor was identified in a Japanese macaque. This skin neoplasm exhibited unique growth patterns and cellular characteristics, offering insights into comparative oncology.
Area of Science:
- Veterinary Pathology
- Comparative Oncology
- Primate Dermatology
Background:
- Basal cell tumors are uncommon in non-human primates.
- This study documents a rare instance in a wild-caught Japanese macaque (Macaca fuscata).
Observation:
- A basal cell tumor was observed in the dermis and subcutis.
- The tumor displayed ribbon, solid, glandular, and cystic patterns.
- Histological examination revealed hyperchromatic nuclei and common mitotic figures.
Findings:
- Immunohistochemistry showed positive reactions for epithelial membrane antigen, keratin, and cytokeratin AE3.
- Electron microscopy indicated the presence of tonofilaments in tumor cells.
- The tumor was demarcated by a fibrous connective tissue capsule.
Implications:
- This case contributes to the understanding of skin neoplasms in non-human primates.
- Provides data for comparative studies on basal cell tumors across species.
- Highlights the importance of dermatological surveillance in wild primate populations.