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Limb saving surgery in bone tumours: experiences in Hungary
M Szendrói1, T Vizkelety, I Antal
1Department of Orthopaedics, Semmelweis University Medical School, Budapest, Hungary.
Summary
Limb salvage surgery is effective for selected early-stage bone tumors. This review of 75 patients shows good survival rates, especially for low-grade tumors, with manageable complications from prostheses or grafts.
Area of Science:
- Orthopaedic Surgery
- Oncology
- Musculoskeletal Tumors
Background:
- Bone tumors require effective treatment strategies to improve patient outcomes.
- Limb salvage surgery (LSS) offers an alternative to amputation for bone tumor management.
- Assessing the efficacy and complications of LSS is crucial for clinical decision-making.
Purpose of the Study:
- To evaluate the outcomes of limb salvage operations for low- and high-grade bone tumors.
- To analyze survival rates, local recurrence, and complications associated with LSS.
- To determine the suitability of LSS in conjunction with chemotherapy for bone cancer treatment.
Main Methods:
- Retrospective clinical review of 75 patients with bone tumors (28 low-grade, 47 high-grade).
- Patients underwent limb salvage surgery with a mean follow-up of 37.2 months.
- Data collected on tumor stage, treatment, survival, recurrence, and complications.
Main Results:
- Overall 3-year survival rates: 97% (low-grade), 84% (osteosarcomas), 50% (Ewing's sarcomas).
- Local recurrence rate was 14%.
- Complications: 2/25 (8%) with tumor prostheses, 13/50 (26%) with autografts/allografts.
Conclusions:
- Limb salvage surgery is an acceptable treatment for selected early-stage bone tumors.
- Successful outcomes depend on early diagnosis and response to chemotherapy.
- Careful patient selection and management of reconstructive methods are essential.